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3D functional models of monkey brain through elastic registration of histological sections

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dc.contributor.author Bettio, Fabio
dc.contributor.author Frexia, Francesca
dc.contributor.author Giachetti, Andrea
dc.contributor.author Gobbetti, Enrico
dc.contributor.author Pintore, Giovanni
dc.contributor.author Zanetti, Gianluigi
dc.date.accessioned 2014-04-17T07:57:47Z
dc.date.available 2014-04-17T07:57:47Z
dc.date.issued 2005-09
dc.identifier.isbn 978-3-540-28869-5 IT
dc.identifier.uri http://hdl.handle.net/11050/815
dc.description.abstract In this paper we describe a method for the reconstruction and visualization of functional models of monkey brains. Models are built through the registration of high resolution images obtained from the scanning of histological sections with reference photos taken during the brain slicing. From the histological sections it is also possible to acquire specifically activated neuron coordinates introducing functional information in the model. Due to the specific nature of the images (texture information is useless and the sections could be deformed when they were cut and placed on glass) we solved the registration problem by extracting corresponding cerebral cortex borders (extracted with a snake algorithm), and computing from their deformation an image transform modeled as an affine deformation plus a non-linear field evaluated as an elastically constrained deformation minimizing contour distances. Registered images and contours are used then to build 3D models of specific brains by a software tool allowing the interactive visualization of cortical volumes together with the spatially referenced neurons classified and differently colored according to their functionalities. IT
dc.language.iso en IT
dc.publisher Springer IT
dc.relation.ispartof Image Analysis and Processing – ICIAP 2005. 13th International Conference, Cagliari, Italy, September 6-8, 2005, Proceedings IT
dc.subject 3D visualization IT
dc.subject monkey brain IT
dc.subject 3D model IT
dc.title 3D functional models of monkey brain through elastic registration of histological sections IT
dc.type Contributo in un libro IT
dc.relation.issue 3617 IT
dc.relation.volume Lecture Notes in Computer Science IT
dc.subject.een-cordis EEN CORDIS::ELETTRONICA, INFORMATICA E TELECOMUNICAZIONI::Multimedia::Visualizzazione, realtà virtuale IT
dc.subject.een-cordis EEN CORDIS::ELETTRONICA, INFORMATICA E TELECOMUNICAZIONI::IT e applicazioni telematiche::Applicazioni per la salute IT
dc.subject.program Program::Data Fusion::Visual Computing (VIC) IT

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